Repetitive transcranial magnetic stimulation is an effective treatment option for treatment resistant depressive disorder. The presented case suggests that repetitive transcranial magnetic stimulation might be effective in inhibition of binge eating and purging behaviors. This case suggests that left dorsolateral prefrontal stimulation with high frequency repetitive transcranial magnetic stimulation could be a potential treatment option for bulimia nervosa comorbid with depressive disorder

Repeated transcranial magnetic stimulation (rTMS) is a non-invasive brain stimulation method that may be preferred as an augmentation strategy for psychiatric patients who may not have responded well enough to psychotropic drugs. In psychoses rTMS may act via changing cortical excitability, connectivity and plasticity. rTMS may induce transcallosal inhibition and antipsychotic drugs may extend the duration of this inhibition. We present a first episode psychosis patient initially unresponsive to antipsychotic treatment, in whom 20 sessions of right 1Hz rTMS augmentation resulted in clinical response and who remained in remission by the 8th month of treatment. We suggest that rTMS is a well-tolerated treatment that may not be reserved only for treatment resistant patients but may also be considered early on in the management of psychiatric disorders.

In this case we report the efficacy of repetitive transcranial magnetic stimulation for treatment resistant auditory verbal hallucinations. The majority of protocols have utilized low-frequency suppressive repetitive transcranial magnetic stimulation over the left temporoparietal cortex with some therapeutic benefits in ameliorating auditory hallucinations. Normalizing the functional connectivity between the temporoparietal and frontal brain regions may underlie the therapeutic effect of repetitive transcranial magnetic stimulation on auditory hallucinations in schizophrenia. Regarding side effects, the rTMS intervention was well tolerated in this case. Future research must focus on the optimum stimulation site and parameters.

Patients with anxiety spectrum disorders are a highly heterogeneous group, requiring new therapeutic strategies and individualized treatment monitoring. Today, there is a growing interest for implementing biological approaches to clinical practice in psychiatry. Quantitative EEG is an excellent tool in this regard, though it has been widely underestimated when compared to recent neuroimaging techniques. In this case series, we presented four cases with a different diagnosis of anxiety spectrum disorder and evaluated their qEEG changes before and after the treatment. In addition, we also calculated the so-called EEG cordance values as an index of cerebral perfusion and cingulate cortex activity. According to the results, there appears to be an increase in the frontal beta and theta band in our cases, which has responded to treatment. In regards to the cordance values, we found that there was a reduction in the prefrontal regions up to %38 percent following the treatment. Based on previous studies, this may also indirectly suggest reduction in the cingulate cortex activity. The possible implications of these findings were discussed. Taken together, this case series highlighted the potential use of qEEG power values, normative z-scores and cordance values in treatment response monitoring of anxiety spectrum disorders.