This is an approach proposal to the assessment and extinction predictability, through a “Brain electro-Activity Map” to Culture, Biases, Brain Washing, Behavior Changing, Public Opinion and similar.
In this paper, we tried to propose an approach through a “Brain Electro Activity Map” to predict the assessment and modification possibility of Culture, Biases, Brain Washing, Behavior Changing, Public Opinion and similar. Because according our opinion, technically there is not any Neuro-Physiological difference between their acquisition and extinction.
We introduced some new concepts which are “flexophrenia-sclerophrenia” and “facilitated and automated connectomes” which are always in need of expression-activity with strongly invasive components.
Then by the combination of the above three concepts, with the well-known old “need of stimulation” (which is an implicit form of accepting the presence of a ”need of activity-expression”), we asserted that all the above mentioned behavioral patterns’ onsets, durations, resistances, changes, can be approached, predicted and changed, in a similar way to each other’s and, can be traced as well, through the implementation of the “Brain Electro Activity Map”

Chronic pain has various forms such as inflammatory pain, visceral pain, headache, disk-related pain, neuropathic pain, cancer pain. Although the biological basis of chronic pain is related to vulnerability, it continues with behavioral and psychological components. In the context of multimodal interventions, interventions other than systemic pharmacologic treatments for chronic pain are also present. Besides interventional approaches; there are several noninvasive options including cognitive behavioral therapy, biofeedback, relaxation therapy, physical therapy, thermal applications, spinal cord stimulation and transcutaneous electrical stimulation. The neuroscientific approach to pain can only be achieved by combining physical and mental components of the pain with neuroscience

In this paper, we tried to explain, what can eventually be the underlying mechanisms of ECT, TMS, tDCS and similar techniques. And tried to explain how, by making some slight changes in the use of the EMW (electromagnetically induced wave) devices, and by integrating them with psychotherapies and pharmacotherapies, we can either better understand their real effectiveness and, design better therapeutic strategies, and increase their positive results. So far, it seems that because of the implemented insufficient designs, either in evaluating the results or, in planning their applications, their positive effects, do not seem to be fully discovered yet

Mobile technologies are transforming our lives. Utilizing the mobile technologies in health care has developed into a new interdisciplinary field called mobile health (mHealth). Data about an individual's moods, cognitions, physical and social activities can be collected and can be used to track mental health of individuals, or make other predictions about their lifestyle such as eating habits and obesity. The smartphone accelerometers and GPS localization systems give information on the overall level of activity. The microphone is used for activity recognition, based on the sound sensed. The social interaction can be tracked by the log of calls, the number of people contacted. Voice analysis is a way of tracking the mood by analyzing the patient's speech during voice calls. The mental health professional must recognize the increasing availability of mobile phones however patient’s motivation to use the applications must also be taken into account. Mobile sensors can assist users to monitor their emotions and behaviors. Mobile technology has the potential to transform mental health care.

The common feature of somatoform disorders is the presence of somatic symptoms that cannot be explained by a general medical condition. Pain disorder is also among the somatoform disorders. 
Pain is defined as an unpleasant sensation occuring as a consequence of a disease, injury or an organic pathology. Breuer and Freud, in their studies on hysteria, suggested that pain could be a manifestation of a psychological problem. The lifetime prevalence is not precisely known. In the Turkish mental health study 12 month incidence of pain disorder is found to be % 11.3 among women , % 4.8 among men and % 8.4 in the general population. The cultural diversity of the mental illnesses particularly somatic symptoms is noticed. Traditions and belief systems influence the formation, presentation and the managemant of dissociative and somatoform symptoms. Types of somatic symptoms differ across the cultures. Higher rates of somatic complaints are found in South America, Asia, particularly in developing countries.
The seperation between physical and emotional experience occurs precisely in Western countires. Thus somatic symptoms are rarely seen in Western culture.

Dementia and stroke are the major health problem often occurs in older individuals aged 65 or more. There are many studies confirm that cholesterol might be involved in the pathogenesis of dementia and stroke. Atorvastatin, broadly used to lower cholesterol in coronary heart disease, are viable medications in decreasing the danger of dementia and stroke. Use of atorvastatin for prolonged period seems to be effective for the prevention of dementia and stroke. The objective of this review is to focuses the pharmacological benefit of atorvastatin in dementia and stroke.

Treating monogenic disorders via gene therapy although still considered experimental by some, has becoming a more accepted method lately especially in these last 10 years with a number of recent clinical successes. Genetic modifications are becoming easier to perform with the progressing technology and discovery of new techniques such as the Clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR associated protein 9 (Cas9) methods which can modify DNA with great ease and accuracy. Gene therapy is a powerful technique with huge potential to treat psychiatric and neurodegenerative disorders including Alzheimer’s and Parkinson’s disease. Gene therapy is simple in principle, which is corrective genetic material is sent into cells and the disease is cured by ending the problem at its source. Viral and non-viral vectors which are used for the delivery of the desired genes to the targeted cells are briefly listed and explained. Unlike viral vectors non-viral vectors don’t cause an immune response but their pretty low transfer rate makes them rather less interesting for research. Viral vectors of adenoviruses, adeno-associated viruses, retroviruses with its subclass of lentiviruses and herpes viruses are compared with their advantages and disadvantages related to usage in brain and CNS treatment of our topic. Neurotrophic factors (NTFs) have important roles in brain and nervous tissue. Delivering NTFs via viral vectors for treating neurodegenerative diseases is a promising approach. Providing information about principles, methods, hurdles and clinical applications of gene therapy with its historic background to present it with its all basic details and therapeutic effects it can provide to problems related to brain are aimed in this writing.

Deep brain stem lesions have previously been considered unresectable. With the development of tailored skull base approaches, detailed knowledge of topographical anatomy, utilization of intra-operative mapping, identification of safe entry zones, extensive arachnoid dissection, cautious handling of neurovascular structures, modern surgical techniques with minimal compression of brain stem and retractor-less surgery, the resection of these previously unresectable lesions, has become possible. Herewithin, an overall review is provided and illustrative cases are presented with detailed discussion of the technical perspective of each approach and resection.

Trichotillomania is a chronic mental disorder characterized by recurrent hair-pulling. Hoarding, excoriation and trichotillomania are classified as obsessive-compulsive related disorders in DSM-5, which share similar clinical presentations, characterized by inappropriate and excessive repetitive behaviors and dysregulation of inhibitory control processes. Research evidence suggests that abnormalities in the cortico-striato-thalamic-cortical circuits are one of the key factors underlying the pathophysiology of obsessivecompulsive related disorders, including trichotillomania. Glutamate is the primary neurotransmitter within the cortico-striato-thalamiccortical circuits. Therefore, the use of glutamate-modulating agents is subject to interest for obsessive-compulsive related disorders. N-acetylcysteine, a derivate of the amino acid L-cysteine, has been explored as potential therapy for obsessive-compulsive related disorders, including trichotillomania. Pharmacotherapies that target the prefrontal glutamatergic system, such as N-acetylcysteine, may correct the underlying pathophysiologic abnormalities and symptoms of trichotillomania. Even a limited number of studies are suggesting that N-acetylcysteine is a promising treatment option, these studies did not assess treatment effects exceeding 3-4 months treatment period. Longer term effects of N-acetylcysteine therapy in trichotillomania require further evaluation.

In this article, has been discussed the characteristics that make knowledge unforgettable. The attention has been attracted to the role of the involvement of multiple brain layers, locations and connections, in learning and performing process. It is sustained that “learning and performing are systemic issues” and proposed that “a successful learning and performance is directly proportional to the sum of created appropriate personal ties – created personal functional connectomes - in the entirety of the central nervous system” and the “strength or weakness of a learned material is directly proportional to the quantity, quality and intensity of the ties made within the entire Central Nervous System Network”. In other terms; the more brain parts are involved the better is learned and performed. And, it has been outlined that “the same fact is the explanation of why in different subjects, the memory storages are relatively in different localities, and in vague concentrations.”